电子鼻技术用于检测乳腺癌、肺癌和结直肠癌挥发性气体综述
breath based volatile organic compounds in the detection of breast, lung, and colorectal cancers: a systematic review
电子鼻技术用于检测乳腺癌、肺癌和结直肠癌挥发性气体综述
ingrid oakley-girvan and sharon watkins davis
cancer prevention institute of california, fremont, ca, usa
abstract.
background: detecting volatile organic compounds (vocs) could provide a rapid, noninvasive, and inexpensive screenin tool for detecting cancer.
背景：检测挥发性有机化合物(voc)可以提供一种快速、无创、廉价的癌症筛查工具。
objective: in this systematic review, we identified specific exhaled breath vocs correlated with lung, colorectal, and breast cancer.
目的：在本系统综述中，我们确定了与肺癌、结直肠癌和乳腺癌相关的特定呼气voc。
methods:we identified relevant studies published in 2015 and 2016 by searching pubmed and web of science. the protocol for this systematic review was registered in prospero and the prisma guidelines were used in reporting. vocs and performance data were extracted.
方法：通过检索pubmed和web of science对2015年和2016年发表的相关研究进行鉴定。该系统性审查的方案已在prospero注册，报告中使用了prisma指南。提取挥发性有机化合物和性能数据。
results:three hundred and thirty three records were identified and 43 papers were included in the review, of which 20 were review articles themselves. we identified 17 studies that listed the vocs with at least a subset of statistics on detection cutoff levels, sensitivity, specificity, area under the receiver operating characteristic curve (auc), and gradient.
结果：共鉴定出333份病历，43篇论文，其中20篇为综述文章。我们确定了17项研究，列出了voc，其中至少包含检测截止水平、灵敏度、特异性、传感器工作特性曲线下面积(auc)和梯度统计数据集。
conclusions:breath analysis for cancer screening and early detection shows promise, because samples can be collected easily, safely, and frequently. while gas chromatography-mass spectrometry is considered the gold standard for identifying specific vocs, breath analysis has moved into analyzing patterns of vocs using a variety of different multiple sensor techniques, such as enoses and nanomaterials. further development of vocs for early cancer detection requires clinical trials with standardized breath sampling methods.
结论：呼吸分析在癌症筛查和早期检测中具有应用前景，因为可以方便、安全、频繁地采集样本。虽然气相色谱-质谱法被认为是识别特定voc的金标准，但呼吸分析已经开始使用各种不同的多传感器技术(如enose和纳米材料)分析voc的模式。为了进一步开发用于早期癌症检测的挥发性有机化合物，需要采用标准化呼吸取样方法进行临床试验
keywords:exhaled breath, volatile organic compounds (vocs), biomarkers, lung cancer, colorectal cancer, breast cancer
关键词：呼气、挥发性有机物(vocs)、生物标志物、肺癌、结直肠癌、乳腺癌
众有设备*进入中国航天系统之航天材料及工艺技术研究院
EL3004-倍福数据手册
多功能汽油播种施肥播种机
螺带真空干燥机可实现全过程连续操作
SITEMA安全制动器抱闸介绍
电子鼻技术用于检测乳腺癌、肺癌和结直肠癌挥发性气体综述
等离子清洗机，玻璃处理
PH（ORP）变送器或PH（ORP）仪表的信号隔离器的工作原理、功能及选型
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日处理5吨餐厅餐饮湿垃圾处理器制造厂家
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智能养老社区检测多功能自助体检仪HW-900A
电子鼻技术用于检测乳腺癌、肺癌和结直肠癌挥发性气体综述
ingrid oakley-girvan and sharon watkins davis
cancer prevention institute of california, fremont, ca, usa
abstract.
background: detecting volatile organic compounds (vocs) could provide a rapid, noninvasive, and inexpensive screenin tool for detecting cancer.
背景：检测挥发性有机化合物(voc)可以提供一种快速、无创、廉价的癌症筛查工具。
objective: in this systematic review, we identified specific exhaled breath vocs correlated with lung, colorectal, and breast cancer.
目的：在本系统综述中，我们确定了与肺癌、结直肠癌和乳腺癌相关的特定呼气voc。
methods:we identified relevant studies published in 2015 and 2016 by searching pubmed and web of science. the protocol for this systematic review was registered in prospero and the prisma guidelines were used in reporting. vocs and performance data were extracted.
方法：通过检索pubmed和web of science对2015年和2016年发表的相关研究进行鉴定。该系统性审查的方案已在prospero注册，报告中使用了prisma指南。提取挥发性有机化合物和性能数据。
results:three hundred and thirty three records were identified and 43 papers were included in the review, of which 20 were review articles themselves. we identified 17 studies that listed the vocs with at least a subset of statistics on detection cutoff levels, sensitivity, specificity, area under the receiver operating characteristic curve (auc), and gradient.
结果：共鉴定出333份病历，43篇论文，其中20篇为综述文章。我们确定了17项研究，列出了voc，其中至少包含检测截止水平、灵敏度、特异性、传感器工作特性曲线下面积(auc)和梯度统计数据集。
conclusions:breath analysis for cancer screening and early detection shows promise, because samples can be collected easily, safely, and frequently. while gas chromatography-mass spectrometry is considered the gold standard for identifying specific vocs, breath analysis has moved into analyzing patterns of vocs using a variety of different multiple sensor techniques, such as enoses and nanomaterials. further development of vocs for early cancer detection requires clinical trials with standardized breath sampling methods.
结论：呼吸分析在癌症筛查和早期检测中具有应用前景，因为可以方便、安全、频繁地采集样本。虽然气相色谱-质谱法被认为是识别特定voc的金标准，但呼吸分析已经开始使用各种不同的多传感器技术(如enose和纳米材料)分析voc的模式。为了进一步开发用于早期癌症检测的挥发性有机化合物，需要采用标准化呼吸取样方法进行临床试验
keywords:exhaled breath, volatile organic compounds (vocs), biomarkers, lung cancer, colorectal cancer, breast cancer
关键词：呼气、挥发性有机物(vocs)、生物标志物、肺癌、结直肠癌、乳腺癌
众有设备*进入中国航天系统之航天材料及工艺技术研究院
EL3004-倍福数据手册
多功能汽油播种施肥播种机
螺带真空干燥机可实现全过程连续操作
SITEMA安全制动器抱闸介绍
电子鼻技术用于检测乳腺癌、肺癌和结直肠癌挥发性气体综述
等离子清洗机，玻璃处理
PH（ORP）变送器或PH（ORP）仪表的信号隔离器的工作原理、功能及选型
QJ型深井潜水泵使用方法与维护保养
海德汉LC493F/50nm/ML1240/30mm光栅尺
浅谈罐头杀菌锅的三种杀菌方法
市场上离心玻璃棉卷毡现在多少钱一立方？价格咨询
德国图尔克TURCK超声波传感器工作原理
食品安全国家标准 食品添加剂 薰衣草油 - 相对密度和折光指数
药用铝质软管涂层柔性和粘附力装置
97564-91-5扇贝毒素2标准物质CRM-PTX2-b
垃圾渗滤液处理设备让“浊液”变清
日处理5吨餐厅餐饮湿垃圾处理器制造厂家
铣床实现复合加工工艺诀窍的案例分析
智能养老社区检测多功能自助体检仪HW-900A